John Lees' blog
Pathogens, informatics and modelling at EMBL-EBI
23andme is a service which types 602352 sites on your chromosomal DNA and your mtDNA. It is possible, by comparing to a reference panel in which all sites have been typed, to impute (fill in statistically) the missing sites and thus get an ’estimation’ of your whole genome.
The piece of software impute2 written by B. N. Howie, P. Donnelly, and J. Marchini gives good accuracy when using the 1000 Genome Project as a reference.
Since October 2013 I have stopped using Fedora, and instead use machines running Ubuntu 12.04/13.10, Windows 8 and OS X 10.8.5. As these OSs have a larger user base than Fedora, many of the issues I encounter are well documented and easy to fix (i.e. there is a stackexchange post as one of the top three google results), hence there haven’t been many things for me to post under the original remit of this blog.
Couldn’t easily find a derivation of the sum:
The result is on wikipedia (http://en.wikipedia.org/wiki/List_of_mathematical_series) but the derivation is not. Here is a version I wrote out quickly (click for full size):
This isn’t really a specific question, but I needed to make a bibliography in latex with the following requirements:
The citations take up as little space as possible, so should probably be superscript The citations should be correctly grouped (i.e. 1-3, 6 not 6, 2, 3, 1) The bibliography can take up any amount of space The citations should be linked to their bibliography entry (i.e. hyperref compatible) bib entries contain unicode characters I want the entries to look like the Elsevier standard, though Nature is also fine I want DOIs, properly displayed and hyperlinked, not monospaced The style=nature option supplied to biblatex in the preamble (see http://ctan.
Using chemfig I was able to represent DPPC (Dipalmitoylphosphatidylcholine) and other lipids in Latex by using the following code
\newcommand\setpolymerdelim\[2\]{\def\delimleft{#1}\def\delimright{#2}} \def\makebraces\[#1,#2\]#3#4#5{% \edef\delimhalfdim{\the\dimexpr(#1+#2)/2}% \edef\delimvshift{\the\dimexpr(#1-#2)/2}% \chemmove{% \node\[at=(#4),yshift=(\delimvshift)\] {$\left\delimleft\vrule height\delimhalfdim depth\delimhalfdim width0pt\right.$};% \node\[at=(#5),yshift=(\delimvshift)\] {$\left.\vrule height\delimhalfdim depth\delimhalfdim width0pt\right\delimright_{\rlap{$\scriptstyle#3$}}$};}} _\setpolymerdelim\[\]_ \begin{figure} \small \setatomsep{1.5em} \chemfig{N^+(-\[:180,1.1\]H_3C)(-\[:90,1.3\]CH_3)(-\[:270,1.3\]CH_3)(-\[:-30\]-\[:30\]-\[:-30\]O-\[:30,1.3\]P^+(<\[:50,1.5\]O\rlap{${}^-$})(<:\[:130,1.5\]O\rlap{${}^-$})(-#(1pt,)\[:330,1.3\]O-\[:30\]-\[:-30\](-\[:270\]O-\[:-30\](=\[:270\]O)(-\[@{downleft,0.8}:30\]CH_2-#(1pt,1pt)\[@{downright,0.3}:-30,1.2\]CH_3))(-\[:30\]-\[:-30\]O-\[:30\](=\[:90\]O)(-\[@{upleft,0.8}:-30\]CH_2-#(1pt,1pt)\[@{upright,0.3}:30,1.2\]CH_3))))} \makebraces\[10pt,13pt\]{n}{downleft}{downright} \makebraces\[6pt,15pt\]{n}{upleft}{upright} \label{fig:lipids} \end{figure} The crucial line is: \chemfig{N^+(-\[:180,1.1\]H_3C)(-\[:90,1.3\]CH_3)(-\[:270,1.3\]CH_3)(-\[:-30\]-\[:30\]-\[:-30\]O-\[:30,1.3\]P^+(<\[:50,1.5\]O\rlap{${}^-$})(<:\[:130,1.5\]O\rlap{${}^-$})(-#(1pt,)\[:330,1.3\]O-\[:30\]-\[:-30\](-\[:270\]O-\[:-30\](=\[:270\]O)(-\[@{downleft,0.8}:30\]CH_2-#(1pt,1pt)\[@{downright,0.3}:-30,1.2\]CH_3))(-\[:30\]-\[:-30\]O-\[:30\](=\[:90\]O)(-\[@{upleft,0.8}:-30\]CH_2-#(1pt,1pt)\[@{upright,0.3}:30,1.2\]CH_3))))}
You’ll also need to include the following in the preamble
\usepackage{chemfig} Which produces something that looks like this:
The new Android phones no longer work as USB mass storage devices, and instead use MTP. Not that I really know what this is, or its advantages over the previous system.
Fortunately a very helpful blog post at http://tacticalvim.wordpress.com/2012/12/08/mounting-nexus-4-via-mtp-in-fedora-17/ guided me most of the way (the nexus 4 and galaxy S3 are very similar) I had to make a couple of changes as the device ids were different, but it’s essentially the same instructions so have a look there first